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How to Spot Nail Melanoma

How to Spot Nail Melanoma

March 14, 2025 by Josh Kew

2.1k Views

A Podiatrist’s Guide to Catching This Silent Threat

As a podiatrist, I spend my days knee-deep (or should I say toe-deep?) in everything from ingrown toenails to verrucas. But every so often, I see something far more sinister, something that could quite literally be a matter of life or death: nail melanoma. The challenge? Many people don’t know how to spot nail melanoma, making early detection difficult and increasing the risk of late diagnosis.

Now, I know what you’re thinking. “Melanoma? In the nail?” Yes, it happens. It is what famous musician Bob Marley suffered from and what led to his unfortunate passing. And the tricky part? It’s shockingly easy to miss. That’s why whether you’re a fellow podiatrist, a nail technician, or just someone who loves a good pedicure, you need to know what to look out for.

So, let’s get into it—what does nail melanoma look like, and when should you be sending that client or patient straight to a dermatologist?

What Exactly Is Nail Melanoma & How Can You Spot It?

Nail melanoma (or subungual melanoma, if we’re getting fancy) is a rare but aggressive type of skin cancer that forms under the nail. It often starts in the nail matrix (the hidden part under the cuticle), which makes it difficult to detect in its early stages.

Unlike the more common superficial spreading melanoma that you might see on sun-exposed skin, nail melanoma doesn’t need sunlight to thrive. It’s sneaky, slow-growing, and often ignored until it’s too late.

How to Spot Nail Melanoma: The Subtle Signs You Might Miss

Here’s where things get tricky. Nail melanoma can masquerade as a bruise, fungal infection, or even just a natural pigmentation change—especially in people with darker skin tones, where nail pigmentation is more common. However, it is crucial to remember: never attempt to self-diagnose a nail melanoma. If you notice any of these changes and are unsure, seek medical evaluation rather than assuming it is harmless. Early professional assessment could be life-saving. Key Signs to Watch For:

1. A Dark Streak That Doesn’t Grow Out

A dark brown or black stripe running vertically down the nail is the most common sign. But here’s the catch—it doesn’t move up or grow out as the nail does. If that “bruise” isn’t budging after a few months, it’s time to investigate.

2. Pigment That Extends Onto the Skin (Hutchinson’s Sign)

If the pigmentation spills over onto the cuticle or surrounding skin (called Hutchinson’s sign), consider it a red flag. This is a classic sign of melanoma creeping beyond the nail plate.

3. A New or Changing Nail Streak

If someone has had a faint nail streak for years without any change, it’s probably benign. But if a new streak appears, gets wider, darkens, or changes shape, that’s when alarm bells should start ringing.

4. Nail Dystrophy or Destruction

Melanoma doesn’t always stay neatly under the nail—it can distort, split, or destroy the nail plate. If a nail is lifting, crumbling, or disintegrating without obvious trauma or infection, you need to dig deeper (not literally, please).

5. A Persistent “Infection” That Won’t Clear

Think it’s a fungal nail? Maybe. But if antifungals aren’t working, and the nail is getting worse, reconsider your diagnosis. Melanoma can sometimes mimic onychomycosis (fungal nails), and mistaking the two can delay life-saving treatment.

6. Pain, Bleeding, or a Lumpy Growth Under the Nail

Melanoma doesn’t always come in neat, stripey packages. It can present as a lump, ulceration, or spontaneous bleeding under the nail. If a client says, “I don’t remember injuring it, but it just won’t stop bleeding,” take it seriously.

Who’s at Risk?

Melanoma doesn’t discriminate, but some people are at higher risk than others:

  • People with darker skin tones (they’re more likely to develop subungual melanoma than fair-skinned individuals).
  • Those with a history of trauma to the nail (though it’s not always linked).
  • Individuals with a family history of melanoma.
  • Individuals who spend time in the sun without sunscreen.
  • Anyone over 50 (though it can occur at any age).

When to Refer? How to Spot Nail Melanoma & Act Fast

If you are a practitioner or technician and spot any of the warning signs above, do not hesitate—always refer to a medical doctor (MD) or dermatologist immediately. A delay in diagnosis significantly increases the risk of melanoma spreading, making early referral critical. Even if you are uncertain, it is far better to be overly cautious than to miss a potentially life-threatening condition.

Urgent Referrals Should Happen When:

  • A new or changing dark streak appears, especially in one nail.
  • Pigmentation extends onto the skin (Hutchinson’s sign).
  • The nail is lifting, breaking, or ulcerating without a clear cause.
  • There’s a persistent “infection” that doesn’t respond to treatment.
  • A nail lesion is painful, bleeding, or rapidly changing.

Time is of the essence. Melanoma under the nail is often diagnosed late, meaning it has a higher risk of spreading (metastasising). Learning to spot nail melanoma early, whether you’re a podiatrist, nail technician, or simply monitoring your own health, could be life-saving.

Final Thoughts: Trust Your Gut

If something about a nail doesn’t sit right with you, refer it. No one will fault you for being cautious—but missing a melanoma could have devastating consequences.

For podiatrists and nail techs, we’re often the first line of defence. The average person isn’t inspecting their own toenails with a magnifying glass, so if we don’t spot it, who will?

So next time you see a stubborn nail streak, don’t dismiss it. It could be a bruise… or it could be something much worse.

And in the world of melanoma, early detection is everything.

Have You Ever Spotted a Suspicious Nail?

If you’ve ever come across a case that turned out to be something serious, let’s talk about it. Awareness saves lives, and the more we share, the better we get at spotting these silent threats.

Stay sharp, stay curious, and keep those nails in check!

Categorised: Nail Anatomy, Nail Conditions

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